The tasks of the project are organized in work packages, units of work with different objectives.

WP1

Microbiome correlates of HIV-1 protection and control

WP2

Modulation of HIV-1 immunotherapy (HTI vaccine)

WP3

HTI vaccine randomized clinical trial

WP4

Gut microbiome correlates of serious AIDS/non-AIDS events

WP5

Impact of antiretroviral therapy in the gut bacterial resistome

WP6

Randomized clinical trials of interventions to modulate the gut microbiome in HIV-1 infected adults

WP7

Data integration and systems biology

WP8

Microbiome-based patient stratification software

WP9

Regulatory aspects

WP10

Management, exploitation and communication activities

WP11

Ethical requirements